Circeif4g3
WebBackground: Circular RNAs (circRNAs), a new group of endogenous non-coding RNAs, plays a crucial role in various types of carcinomas. However, there is still limited … WebJul 2, 2024 · CircEIF4G3 expression was downregulated in patients with GC and predicted poor prognosis. CircEIF4G3 destabilized δ-catenin by forming circEIF4G3/δ …
Circeif4g3
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WebJul 2, 2024 · Mechanistic studies revealed that circEIF4G3 bound to \u03b4-catenin protein to promote its TRIM25-mediated ubiquitin degradation and interacted with miR-4449 to …
WebDec 13, 2024 · Gastric cancer (GC) is the third most common cause of cancer-related death worldwide. Advanced diagnosis and high rates of relapse and metastasis are associated with the poor prognosis of this disease. GC has a complex etiopathogenesis of which the underlying mechanisms remain to be explored. WebCircEIF4G3 destabilizes δ-catenin protein by enhancing TRIM25-mediated ubiquitin degradation and functions as a miRNA sponge to modulate miR-4449/SIK1 axis, which synergistically leads to the ...
WebNov 16, 2024 · We show here that ME-circEIF4G3 is controlled by SRRM4 and, given the down-regulation of SRRM4 in gliomas and association with poor survival outcomes, this … WebOct 24, 2024 · 【1】非编码RNA: 阻断miR-181b和增加Sema3A是房颤治疗干预的潜在策略. 2024-07-25报道，近日，来自长庚纪念医院的研究者们在J Clin Invest.杂志上发表了题为“miR-181b targets semaphorin 3A to mediate TGF-β–induced endothelial-mesenchymal transition related to atrial fibrillation”的文章，该研究提供了转化生长因子-β通过miR-181b ...
Web正式实验上，团队构建了circEIF4G3敲低与过表达的细胞模型，通过体外功能实验（RNA-FISH、细胞增殖与迁移和侵袭检测、细胞凋亡检测）以及体内动物实验（免疫组织化学 …
WebResults Downregulated expression of circular RNA EIF4G3 (circEIF4G3; hsa_circ_0007991) was found in GC and was associated with poor clinical outcomes. Overexpression of circEIF4G3 suppressed GC growth and metastasis through the inhibition of β-catenin signaling, whereas knockdown of circEIF4G3 showed the opposite effects. fnaf charlie\u0027s deathWebJul 2, 2024 · CircEIF4G3 functions as a miR-4449 sponge. (A) RIP assay was applied using Ago2 antibody in GC cells. The relative RNA level of circEIF4G3 was detected by qRT … fnaf charlie x michaelWebAug 10, 2024 · The formation of a unique back-splice junction (BSJ) differentiates the circRNAs from their linear counterpart. CircRNAs are highly expressed in the central nervous system where many of them are regulated during development 1 – 3, inflammation 4, and also found to function as biomarkers in cancer 5 – 7. fnaf charlotte emily wattpadWebhsa_circEIF4G3_060. Last modified by: XXH Created Date: 4/29/2024 8:53:00 AM Other titles: 交集的circRNA Sheet2 ... fnaf charlotte emily ageWebAug 26, 2024 · CircEIF4G3 is expected to be a biomarker and therapeutic target for predicting the prognosis of gastric cancer. By analyzing the Master Gene Expression (GEO) dataset, we identified circRNAs that are differentially expressed in GCs. The researchers explored the biological role of circRNAs in GC through in vitro functional analysis and in … greens scaffolding services ne24WebThe results showed that the expressions of circDDX17, Has_circ_0026344, circVAPA, circNSUN2, circACAP2, circACVRL1 and circEIF4G3 were regulated by 0.8 mmol/L ALO (p<0.001, Figure 3A). Through subsequent screening of target genes, we found that only circNSUN2 and miR-296-5p have targeted binding sites . greens scarboroughWebOct 19, 2024 · CDR1as expression is known to be correlated with hepatic microvascular invasion in HCC tissue and hsa_circ_0000520 (circRPPH1), hsa_circ_0005075 (circEIF4G3), hsa_circ_0066444 (circADAMTS9), and hsa_circ_0001649 (circSRPRH) have all been shown to be expressed at different levels in HCC compared to adjacent normal … greens sculpt nation